Progressive Collapsing Foot Deformity Research Articles

Risk factors for Midfoot arthritis associated with Medical history by Weight Bearing Computed Tomography.

Tarso-metatarsal joints and naviculocuneiform joints comprising midfoot is the second most commonly involved joints following the first metatarsophalangeal joint in the foot. However, related factors of midfoot arthritis (MA) have been rarely reported. The bony structure and alignment can be more precisely assessed using Weight-Bearing Computed Tomography (WBCT) than conventional radiographs. Therefore, the aim of this study was to investigate risk factors for MA related to medical history and comorbid foot deformities using WBCT. WBCT data from September 2014 to April 2022 were extracted from a single referral hospital. All cases were divided into two groups by the presence of MA. Twenty-five potential related factors including demographics, etiology, and common co-occurring foot deformities were collected for comparison. Six hundred six cases (247 males and 359 females) among consecutive 1316 cases between September 2014 to April 2022 were selected. One hundred thirty-nine male cases (56.3%) and 210 female cases (58.5%) showed MA. In stepwise multiple logistic regression analysis, 5 factors remained statistically significant. The multivariate-adjusted odds ratios for age, laterality, body mass index (BMI), Progressive Collapsing Foot Deformity (PCFD), and lesser toe deformities (LTD) were 1.08, 1.54, 1.05, 6.62, and 3.03 respectively. Risk factors for MA associated with medical history and foot deformities included age, laterality, BMI, PCFD, and LDT.Level of Evidence: Level III, retrospective case-control study.

Defining the Patient Acceptable Symptom State Using PROMIS Following Reconstruction of the Progressive Collapsing Foot Deformity

Introduction/Purpose: Although reconstruction of the flexible progressive collapsing foot deformity (PCFD) has been shown to improve patient-reported outcomes (PROs), there is limited data describing postoperative success as defined by patient satisfaction following surgery. Distinct from the minimal clinically important difference (MCID), the patient acceptable symptom state (PASS) is a novel PRO measurement that represents the symptom threshold beyond which patients are satisfied with their postoperative outcome. The primary aim of this study was to use Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function (PF) and Pain Interference (PI) scores in combination with anchor questions to define PASS thresholds following reconstruction of the flexible PCFD. A secondary aim was to analyze how patient-specific variables and certain PCFD reconstruction procedures may impact the probability of reaching PASS thresholds. Methods: Using data collected from a foot and ankle orthopedic registry at a large academic institution, 109 patients who underwent reconstruction of a flexible PCFD between February 2019 and March 2021, had preoperative and 2-year postoperative PROMIS PF and PI scores, and 2-year postoperative responses to two PASS anchor questions (the delighted-terrible scale and the satisfied scale) were included in the study. Patients who underwent either a double or triple arthrodesis were excluded. Patient responses to the anchor questions were dichotomized and receiver operating characteristic (ROC) curve analyses were performed. Using the Youden Index to balance sensitivity and specificity and maximize the area under the curve (AUC), PASS thresholds with 95% confidence intervals were quantified using 2000 bootstrapped iterations. Lastly, multivariable logistic regressions were performed to analyze the influence of patient demographics, preoperative PROMIS scores, and certain PCFD reconstruction procedures on the probability of reaching the PASS thresholds. Results: The PASS threshold for PROMIS PF was found to be 42.6 using both the delighted-terrible and the satisfied scale and 73.4% of patients (80/109) reached the threshold (both AUCs: 0.91) (Table 1). The PASS thresholds for PROMIS PI defined using the delighted-terrible scale and the satisfied scale were 54.5 (AUC: 0.90) and 57.5 (AUC: 0.91), respectively, with 72.5% of patients (79/109) and 81.7% of patients (89/109) meeting the respective thresholds. Neither patient demographics nor specific PCFD reconstruction procedures affected the probability of meeting the PASS thresholds. However, a lower preoperative PROMIS PF score or a higher preoperative PROMIS PI score significantly decreased the probability of achieving the PASS thresholds. Conclusion: Following reconstruction of the flexible PCFD, PASS thresholds for the PROMIS PF and PI domains were found to be lower and higher, respectively, than population norms. This suggests that patients may be satisfied with the outcome of their surgery despite not returning to the population mean. The probability of achieving the PASS thresholds was influenced by both preoperative PROMIS PF and PI scores but not by patient demographics or certain PCFD reconstruction procedures. In addition to guiding future outcomes research, these results may help foot and ankle surgeons optimize treatment for the flexible PCFD and better manage patient expectations.

First Tarsometatarsal Instability Corrects Itself After Triple Arthrodesis in Progressive Collapsing Foot Deformity

Introduction/Purpose: Triple arthrodesis is commonly used to correct severe or rigid progressive collapsing foot deformity (PCFD). In many cases of PCFD, patients have associated first tarsometatarsal instability demonstrated by plantar gapping or dorsal subluxation on the lateral weight-bearing radiographs. During flatfoot reconstruction this is usually addressed with a first tarsometatarsal fusion to realign the joint and to restore the medial column height. However in the setting of triple arthrodesis it has not been well established if it is necessary to add a first tarsometatarsal fusion to the procedure in order to adequately correct the overall deformity. This study retrospectively examined pre- and post-operative radiographs of patients that had first tarsometatarsal instability as a component of their PCFD and who were managed by triple arthrodesis alone. Methods: All triple arthrodesis cases were searched for a single surgeon between 2013 and 2021. Inclusion criteria were patients who had a diagnosis of PCFD and had an isolated triple arthrodesis without first tarsometatarsal joint fusion. Pre-operative radiographs were then examined for the presence of first tarsometatarsal joint instability on the lateral weight-bearing view only. This was demonstrated by either plantar gapping or first metatarsal dorsal subluxation at the tarsometatarsal joint. Those patients who were a minimum of 21 months post-op were called to obtain current radiographs. Measurement of the sagittal first metatarsal-medial cuneiform angle as well as a the first metatarsal lift as described by King and Toolan (FAI 2004) was performed. Results: Twenty patients satisfied the inclusion criteria and were included in the study. Of these patients, five had no correction of their first tarsometatarsal joint instability postoperatively and were considered failures. The remaining fifteen patients demonstrated early correction of their first tarsometatarsal joint instability and were called back for longer term follow-up radiographs. Average follow-up was 4.8 years (range 1.8 - 9.4 years). The sagittal first metatarsal-medial cuneiform angle (plantar gapping) improved significantly from 3.8 degrees to 1.0 degrees (p=0.00002). The first metatarsal lift (dorsal subluxation) corrected from 4.0 mm to 1.5 mm (p=0.000001). Only one patient showed radiographic evidence of arthritis in the first tarsometatarsal joint at final follow-up. Conclusion: First tarsometatarsal joint fusion to correct medial column instability is well established in flatfoot reconstruction cases. However less is known about whether this is required when performing a triple arthrodesis for PCFD. In this study, 75% of patients had their first tarsometatarsal joint instability correct itself after isolated triple arthrodesis and maintained this correction at 4.8 year follow-up. In many cases of PCFD with medial column instability, triple arthrodesis alone may be adequate to restore overall alignment thereby avoiding the additional operative time and risk for complication associated with a first tarsometatarsal joint fusion. First tarsometatarsal joint instability correction following isolated triple arthrodesis. Pre-operative radiographs demonstrate plantar gapping and dorsal subluxation at the first tarsometatarsal joint consistent with medial column instability. At 2.8 year post-operative follow up after isolated triple arthrodesis, radiographs show maintained correction of the instability.

Defining the patient acceptable symptom state using PROMIS following reconstruction of the progressive collapsing foot deformity

BackgroundThe patient acceptable symptom state (PASS) represents the threshold beyond which patients are satisfied with their outcome. This study aimed to define PASS thresholds for progressive collapsing foot deformity (PCFD) reconstruction using Patient-Reported Outcomes Measurement Information System (PROMIS) scores and anchor question responses. MethodsThis retrospective study consisted of 109 patients who underwent flexible PCFD reconstruction, had preoperative and 2-year postoperative PROMIS scores, and 2-year postoperative anchor question responses. ROC curve analyses were performed to quantify PASS thresholds. ResultsPASS thresholds for the PROMIS Physical Function (PF) and Pain Interference (PI) domains were found to be lower and higher, respectively, than population norms. Furthermore, patients with higher preoperative PROMIS PF scores or lower preoperative PROMIS PI scores had a significantly higher likelihood of achieving the PASS thresholds. ConclusionIn addition to guiding future outcomes research, these results may help surgeons optimize treatment for PCFD and better manage patient expectations. Level of evidenceIII, retrospective cohort study

Peroneus Brevis to Longus Tendon Transfer in the Treatment of Flexible Progressive Collapsing Foot Deformity: A Cadaveric Study.

Although operative treatment of the flexible progressive collapsing foot deformity (PCFD) remains controversial, correction of residual forefoot varus and stabilization of the medial column are important components of reconstruction. A peroneus brevis (PB) to peroneus longus (PL) tendon transfer has been proposed to address these deformities. The aim of our study was to determine the effect of an isolated PB-to-PL transfer on medial column kinematics and plantar pressures in a simulated PCFD (sPCFD) cadaveric model. The stance phase of level walking was simulated in 10 midtibia cadaveric specimens using a validated 6-degree of freedom robot. Bone motions and plantar pressure were collected in 3 conditions: intact, sPCFD, and after PB-to-PL transfer. The PB-to-PL transfer was performed by transecting the PB and advancing the proximal stump 1 cm into the PL. Outcome measures included the change in joint rotation of the talonavicular, first naviculocuneiform, and first tarsometatarsal joints between conditions. Plantar pressure outcome measures included the maximum force, peak pressure under the first metatarsal, and the lateral-to-medial forefoot average pressure ratio. Compared to the sPCFD condition, the PB-to-PL transfer resulted in significant increases in talonavicular plantarflexion and adduction of 68% and 72%, respectively, during simulated late stance phase. Talonavicular eversion also decreased in simulated late stance by 53%. Relative to the sPCFD condition, the PB-to-PL transfer also resulted in a 17% increase (P = .045) in maximum force and a 45-kPa increase (P = .038) in peak pressure under the first metatarsal, along with a medial shift in forefoot pressure. The results from this cadaver-based simulation suggest that the addition of a PB-to-PL transfer as part of the surgical management of the flexible PCFD may aid in correction of deformity and increase the plantarflexion force under the first metatarsal. This study provides biomechanical evidence to support the addition of a PB-to-PL tendon transfer in the surgical treatment of flexible PCFD.

Passive Eversion Assessment for Progressive Collapsing Foot Deformity After Lateral Column Lengthening: A Cadaveric Biomechanical Study.

Reduced hindfoot eversion motion has been proposed as a cause of increased lateral foot pressure following lateral column lengthening (LCL) for progressive collapsing foot deformity (PCFD). A subjective intraoperative assessment of passive eversion has been suggested to help evaluate correction; however, it is unclear how passive eversion correlates with objective measurements of foot stiffness. Our objectives were to quantify the relationship between the maximum passive eversion in hindfoot joints following LCL with plantar pressure during stance and to determine the influence of wedge size on these outcomes. Ten cadaveric specimens extending from the mid-tibia distally were tested on a 6-degrees-of-freedom robot to simulate the stance phase of level walking. Five conditions were tested: intact, simulated PCFD, and 3 LCL wedge conditions (4, 6, and 8 mm). Outcomes included the lateral-to-medial forefoot plantar pressure (LM) ratio during stance and the maximum passive eversion measured in the hindfoot joints. Simple linear regressions were performed to evaluate relationships between outcomes and wedge sizes. A strong negative relationship was found between passive subtalar eversion and the LM ratio during stance (r[38] = -0.46; p = 0.0007), but not between passive talonavicular eversion and the LM ratio (r[38] = -0.02; p = 0.37). Wedge size was strongly related to subtalar eversion (r[38] = -0.77; p < 0.0001), talonavicular eversion (r[38] = -0.55; p = 0.0003), and the LM ratio (r[38] = 0.70; p < 0.0001). Increased wedge size resulted in average decreases in subtalar and talonavicular eversion of 1.0° (95% confidence interval [CI]: 0.8° to 1.3°) and 1.2° (95% CI: 0.6° to 1.6°), respectively. Increased wedge size also increased the LM ratio by 0.38 (95% CI: 0.25 to 0.50), indicating a lateral shift in plantar pressure. Decreased hindfoot eversion following LCL was related to increased lateral plantar pressure during stance. Increasing wedge size correlated with decreasing passive hindfoot eversion and increasing lateral plantar pressure, suggesting that intraoperative preservation of eversion motion may be important for preventing excessive lateral loading. To avoid overcorrection or undercorrection of the deformity, hindfoot eversion assessment in addition to radiographic evaluation may be important for optimizing the amount of lengthening to achieve successful LCL.

Radiographic Analysis of Valgus Ankle Deformity With or Without Medial Longitudinal Arch Collapse.

Establishing a surgical plan for ankle deformities necessitates a comprehensive understanding of the deforming forces involved, and the morphology of the ankle deformity plays an important role as well. Valgus tibiotalar tilt development has mostly been described in patients with a low medial longitudinal arch, as seen in progressive collapsing foot deformity (PCFD). However, some valgus ankles demonstrate no radiographic evidence of a collapsed medial arch. This study aims to investigate whether there are differences in the radiographic morphology of valgus ankle deformities between patients with and without a low medial longitudinal arch to explore if they have different etiologies. We retrospectively reviewed patients who underwent surgical treatment for asymmetric valgus ankle deformity at our institution between 2017 and 2021. Patients with a valgus tibiotalar tilt (TT) greater than 4 degrees and Meary angle greater than 30 degrees (mean: 38.9) were included in the PCFD group (n = 29). The non-PCFD group (n = 24) with TT greater than 4 degrees and Meary angle less than 4 degrees (mean: 0.3) was also established. In the weightbearing ankle anteroposterior view, the TT and medial distal tibial angle were measured. Additionally, to assess the mediolateral position of the talus, the talar center migration (TCM) and lateral talar dome-plafond distance (LTD-P) ratio in the coronal plane were measured. In weightbearing computed tomography (WBCT), the degree of axial plane talocalcaneal subluxation and the prevalence of sinus tarsi bony impingement were assessed. Intergroup comparison was conducted. Both groups demonstrated a similar degree of TT, with a mean of 11.6 degrees in the PCFD group and 13.7 degrees in the non-PCFD group (P = .2330). However, the PCFD group showed a significantly greater TCM and LTD-P ratio compared with those of the non-PCFD group (P < .0001), indicating that PCFD patients have a more medially translated talus in ankle anteroposterior radiographs. WBCT showed that the PCFD group on average had 18 degrees greater axial plane talocalcaneal subluxation (P < .0001) and 52% higher prevalence of sinus tarsi bony impingement (P = .0002) compared with the non-PCFD group. This study suggests that valgus ankles may exhibit different radiographic morphologies depending on the status of the longitudinal arch. Valgus ankles in PCFD patients tend to have a more medially translated talus. This finding may suggest the presence of different deforming forces between the 2 groups and may indicate the need for different treatment strategies to address talar tilt. Level III, case-control.

Association Between Weightbearing CT and MRI Findings in Progressive Collapsing Foot Deformity.

Weightbearing computed tomography (WBCT) scans allow for a better understanding of foot alignment in patients suffering from progressive collapsing foot deformity (PCFD). However, soft tissue integrity (eg, spring ligament complex or tibialis posterior tendon) cannot be easily assessed via WBCT. As performing both WBCT and magnetic resonance imaging (MRI) might not be cost effective, we aimed to assess whether there is an association between osseous and soft tissue findings in WBCT and MRI. In this observational study, a consecutive cohort of 24 patients of various stages of PCFD (mean age 51 ± 18 years) underwent WBCT scans and MRI. Twenty-four healthy individuals of similar age, body mass index (BMI), and sex with WBCT scans were used as a control group. In addition to of osseous sinus tarsi impingement, 4 commonly used 3-dimensional (3D) measurements (talocalcaneal overlap [TCO], talonavicular coverage [TNC], Meary angle [MA], axial/lateral) were obtained using a dedicated postprocessing software (DISIOR 2.1, Finland) on the WBCT data sets. Sinus tarsi obliteration, spring ligament complex, tibiospring ligament integrity, as well as tibialis posterior tendon degeneration were evaluated with MRI. Statistical analysis was performed for significant (P < .05) correlation between findings. None of the assessed 3D measurements correlated with either spring ligament complex or tibiospring ligament tears. BMI and TCO were found to be associated with tibialis posterior tendon tears. Seventy-five percent of patients with osseous sinus tarsi impingement on WBCT also showed signs of sinus tarsi obliteration on MRI. Although WBCT reflects foot alignment and can reveal osseous sinus tarsi impingement in PCFD patients, the association between WBCT-based 3D measurements and ligament or tendon tears assessed via MRI is limited. WBCT appears complimentary to MRI regarding its diagnostic value. Both imaging options add important information and may impact decision making in the treatment of PCFD patients. Level IV, observational study.

Biomechanical Effects of Subtalar Joint Fusion and Medial Ligament Reconstruction in Simulated Progressive Collapsing Foot Deformity.

The purpose of this study is to investigate the biomechanical effect of medial displacement calcaneal osteotomy (MDCO), subtalar joint fusion (SF), and medial ligament reconstruction (MLR: deltoid-spring ligament) in a severe flatfoot model. We hypothesized that (1) combination of MDCO and SF improves the tibiotalar and foot alignment in severe progressive collapsing foot deformity (PCFD) cadaver model. (2) However, if a residual valgus heel alignment remains after MCDO and SF, it can lead to increased medial ligament strain, foot malalignment, and tibiotalar valgus tilt, which will be mitigated by the addition of MLR. Ten fresh-frozen cadaveric foot specimens were used to create a severe flatfoot model. The foot alignment changes, including the talo-first metatarsal angle in the axial and sagittal planes, subtalar angle, and tibiotalar angle in the coronal plane, were measured. The angles were measured at the initial condition, after creating the severe flatfoot model, and after each successive reconstructive procedure in the following order: (1) MDCO, (2) SF, and (3) MLR. Tibiotalar valgus tilt was decreased with the MDCO procedure: 4.4 vs 1.0 degrees (P = .04). Adding in situ SF to the MDCO led to increased tibiotalar tilt to 2.5 degrees was different from the initial condition (P = .01). Although the tibiotalar valgus tilt was significantly decreased after adding the MLR to the MDCO/SF procedure compared with the severe flatfoot model (0.8 vs 4.4 degrees, P = .03), no significant difference in the tibiotalar valgus tilt was observed between MDCO/SF and MDCO/SF with MLR. Our results demonstrated that MDCO significantly improved forefoot abduction and medial arch alignment, with no significant additional improvement observed with addition of SF. Following SF, a residual valgus heel alignment can contribute to subsequent tibiotalar valgus tilt. The addition of MLR did not show significantly decreased tibiotalar valgus tilt following SF. Residual valgus heel alignment after subtalar joint fusion in the surgical treatment of PCFD can lead to increased medial ligament strain. Although MLR might be considered for providing medial stability, it may not necessarily prevent the development of tibiotalar valgus tilt.

Minimally Invasive Scarf Calcaneal Osteotomy is an Alternative Technique for the Correction of Progressive Collapsing Foot Deformity

Scarf calcaneal osteotomy is an extra-articular procedure to correct progressive collapsing foot deformity (PCFD). As an open approach may display wound healing problems, we herein report a novel method of percutaneously performed minimally invasive scarf calcaneal osteotomy. Twenty patients aged 56.75 ± 7.13 with grade 1AB of PCFD were included. A radiologic assessment was performed before the procedure and after 3 months. Clinical evaluation was done before the procedure, after 3 months, and after 12 months. The Manchester-Oxford Foot Questionnaire and Functional Foot Index score improved from 77.63 ± 11.67 preoperatively to 33.29 ± 18.55 at the follow-up (P &lt; 0.001) and from 69.26 ± 16.32 preoperatively to 32.00 ± 20.35 at the follow-up (P &lt; 0.001), respectively. There was a statistically significant improvement in all radiologic measurements, namely, talonavicular coverage angle from 20.03 ± 5.51 to 14.18 ± 6.49 (P &lt; 0.001), the distance between medial cuneiform and fifth metatarsal from 0.53 ± 3.31 to 6.95 ± 4.01 (P &lt; 0.001), anteroposterior talo-first metatarsal angle from 22.13 ± 7.28 to 17.09 ± 6.87 (P &lt; 0.005), Meary angle from 25.12 ± 2.73 to 15.17 ± 7.06 (P &lt; 0.001), calcaneal inclination angle from 12.23 ± 4.01 to 16.82 ± 5.53 (P &lt; 0.001), navicular height from 15.57 ± 4.10 to 20.57 ± 6.87 (P &lt; 0.005), and tibio-calcaneal angle from −3.79 ± 5.15 to 6.71 ± 4.41 (P &lt; 0.001). In experienced hands, minimally invasive scarf calcaneal osteotomy seems to be an effective and reproducible subtalar preserving surgical technique for PCFD cases with mild midfoot abduction severity. Level of Evidence: Diagnostic Level 4. See Instructions for Authors for a complete description of levels of evidence.

ALTERNATION OF THE 3D SUBTALAR JOINT ALIGNMENT AFTER INFRAMALLEOLAR OSTEOTOMY IN PROGRESSIVE COLLAPSING FLATFOOT DEFORMITY

A medializing calcaneal osteotomy (MCO) is one of the key inframalleolar osteotomies to correct progressive collapsing foot deformity (PCFD). While many studies were able to determine the hind- and midfoot alignment after PCFD correction, the subtalar joint remained obscured by superposition on plain radiography. Therefore, we aimed to perform a 3D measurement assessment of the hind- and subtalar joint alignment pre- compared to post-operatively using weightbearing CT (WBCT) imaging.Fifteen patients with a mean age of 44,3 years (range 17-65yrs) were retrospectively analyzed in a pre-post study design. Inclusion criteria consisted of PCFD deformity correct by MCO and imaged by WBCT. Exclusion criteria were patients who had concomitant midfoot fusions or hindfoot coalitions. Image data were used to generate 3D models and compute the hindfoot - and talocalcaneal angle as well as distance maps.Pre-operative radiographic parameters of the hindfoot and subtalar joint alignment improved significantly relative to the post-operative position (HA, MASa, and MACo). The post-operative talus showed significant inversion, abduction, and dorsiflexion of the talus (2.79° ±1.72, 1.32° ±1.98, 2.11°±1.47) compared to the pre-operative position. The talus shifted significantly different from 0 in the posterior and superior direction (0.62mm ±0.52 and 0.35mm ±0.32). The distance between the talus and calcaneum at the sinus tarsi increased significantly (0.64mm ±0.44).This study found pre-dominantly changes in the sagittal, axial and coronal plane alignment of the subtalar joint, which corresponded to a decompression of the sinus tarsi. These findings demonstrate the amount of alternation in the subtalar joint alignment that can be expected after MCO. However, further studies are needed to determine at what stage a calcaneal lengthening osteotomy or corrective arthrodesis is indicated to obtain a higher degree of subtalar joint alignment correction.

Isolated Talonavicular Arthrodesis as Treatment for Flexible Progressive Collapsing Foot Deformity: A Case Series.

For the younger, more active patient with flexible symptomatic progressive collapsing foot deformity (PCFD), joint-sparing procedures may be preferred to preserve functional motion. Isolated talonavicular (TN) arthrodesis has been described for treatment of rigid and flexible PCFD for patients that are older and less active whose deformity is still correctable through the TN joint. The purpose of this study was to evaluate radiographic and clinical outcomes in patients with PCFD treated with isolated triplanar correction with a TN joint arthrodesis. Forty-nine patients (53 feet) with flexible PCFD underwent isolated TN arthrodesis. Weightbearing radiographs were performed pre- and postoperatively, and measurements included lateral talar-first metatarsal angle, calcaneal pitch, TN coverage angle, and the anteroposterior (AP) talar-first metatarsal angle. The Foot and Ankle Ability Measure (FAAM) and Veterans-Rand 12-Item Health Survey (VR-12) scores were also collected. Thirty-five females and 14 males were evaluated with a mean age of 63 years, at an average follow-up of 41.3 months. Significant improvements were found radiographically. Lateral radiographs demonstrated improvements in lateral talar-first metatarsal angle from 25.2 degrees preoperatively to 9.5 degrees postoperatively (P < .001) and calcaneal pitch from 14.9 degrees preoperatively to 17.5 degrees postoperatively (P < .001). AP radiographs showed the TN coverage angle improving from 35.0 degrees to 4.9 degrees postoperatively (P  < .001) and AP talar-first metatarsal angle improving from 17.3 degrees to 5.9 degrees postoperatively (P < .001). Clinical outcomes were improved in the FAAM pain score (48.6 to 39.2, P = .130), FAAM ADL score (53.8 to 69.2, P = .002), FAAM Sport score (29.5 to 40.7, P = .099), and the overall FAAM score (47.7 to 63.1, P = .006). Patient satisfaction with medical care was 85.2/100 postoperatively. Isolated TN arthrodesis is a viable surgical option for older, lower-demand patients with flexible PCFD. This study demonstrated significant improvements in radiographic alignment and FAAM scores. Comparative studies with other surgical procedures should be performed to determine which is the best technique for older, lower-demand patients with flexible PCFD. Level III, retrospective cohort study.

Talocalcaneal Ligament Reconstruction Kinematic Simulation for Progressive Collapsing Foot Deformity.

In progressive collapsing foot deformity (PCFD), an internal and plantar rotation of the talus relative to the calcaneus may result in painful peritalar subluxation. Medial soft tissue procedures (eg, spring ligament repair) aim to correct the talar position via the navicular bone if bony correction alone is not sufficient. The effect of the medial soft tissue reconstruction on the talar reposition remains unclear. We hypothesized that a subtalar talocalcaneal ligament reconstruction might be favorable in PCFD to correct talar internal malposition directly. This pilot study aims to evaluate the anatomical feasibility and kinematic behavior of a subtalar ligament reconstruction in PCFD. Three-dimensional surface model from 10 healthy ankles were produced. A total of 1089 different potential ligament courses were evaluated in a standardized manner. A motion of inversion/eversion and talar internal/external in relation to the calcaneus were simulated and the ligament strain, expressed as a positive length variation, for each ligament was analyzed. The optimal combination for the ligament reconstruction with increased length in internal rotation of the talus, isometric kinematic behavior in inversion/eversion, and extraarticular insertion on talus and calcaneus was selected. A laterodistal orientation of the talar insertion point in respect to the subtalar joint axis and laterodistal deviation of the calcaneal insertion point presents the highest ligament lengthening in internal talar rotation (+0.56 mm [3.8% of total length]) and presented a near-isometric performance in inversion/eversion (+0.01 to -0.01 mm [0.1% of total length]). This kinematic model shows that a ligament reconstruction in the subtalar space presents a pattern of length variation that may stabilize the internal talar rotation without impeding the physiological subtalar motion. This study investigates the optimal location, feasibility, and kinematic behavior of a ligament reconstruction that could help stabilize peritalar subluxation in progressive collapsing foot deformity.

The Role of the Transverse Arch in Progressive Collapsing Foot Deformity.

The transverse arch (TA) has recently been shown to significantly increase the intrinsic stiffness of the midfoot when coupled with the medial longitudinal arch (MLA). Progressive collapsing foot deformity (PCFD) is a complex deformity that ultimately results in a loss of stiffness and collapse of the MLA. The role of the TA has not been investigated in patients diagnosed with this disorder using weightbearing CT (WBCT). Therefore, this study aims to answer the following questions: (1) Is the curvature of the TA decreased in PCFD? (2) Where within the midfoot does TA curvature flattening happen in PCFD? A retrospective review of weightbearing CT images was conducted for 32 PCFD and 32 control feet. The TA curvature was assessed both indirectly using previously described methods and directly using a novel measurement termed the transverse arch plantar (TAP) angle that assesses the angle formed between the first, second, and fifth metatarsals in the coronal plane. Location of TA collapse was also assessed in the coronal plane. The TAP angle was significantly higher in PCFD (mean 115.2 degrees, SD 10.7) than in the control group (mean 100.8 degrees, SD 7.9) (P < .001). No difference was found using the calculated normalized TA curvature between PCFD (mean 17.1, SD 4.8) and controls (mean 18.3, SD 4.0) (P = .266). Location of collapse along the TA in PCFD was most significant at the second metatarsal and medial cuneiform. The TA is more collapsed in PCFD compared to controls. This collapse was most substantial between the plantar medial cuneiform and the plantar second metatarsal. This may represent a location of uncoupling of the TA and MLA. Level III, retrospective case control.

What’s the clinical significance of VAS, AOFAS, and SF-36 in progressive collapsing foot deformity

BackgroundThis study aimed to ascertain the minimal clinically important difference (MCID), and substantial clinical benefit (SCB) of the American Orthopedic Foot and Ankle Society (AOFAS) scale, visual analog scale (VAS) for pain, and Short Form-36 Health Survey (SF-36) in progressive collapsing foot deformity (PCFD) surgery. MethodsIn this retrospective cohort study, a total of 84 patients with PCFD (84 feet) who underwent surgery between July 2015 and April 2021 were included. The study assessed the patients' subjective perception, as well as their VAS, AOFAS, and SF-36 scores at a minimum two-year follow-up, and these data were subjected to statistical analysis. The study utilized Spearman correlation analysis to determine the degree of correlation between patients' subjective perception and their VAS, AOFAS, and SF-36 scores. The minimal detectable change (MDC), MCID, and SCB for VAS, AOFAS, and SF-36 were calculated using both distribution- and anchor-based methods. The classification outcomes obtained from the distribution- and anchor-based methods were assessed using Cohen’s kappa. ResultsBased on the subjective perception of the patients, a total of 84 individuals were categorized into three groups, with 7 in the no improvement group, 14 in the minimum improvement group, and 63 in the substantial improvement group. Spearman's correlation analysis indicated that the patients' subjective perception exhibited a moderate to strong association with VAS, AOFAS, SF-36 PCS, and SF-36 MCS, with all coefficients exceeding 0.4. The MCID of VAS, AOFAS, SF-36 PCS, and SF-36 MCS in PCFD surgery were determined to be 0.93, 5.84, 4.15, and 4.10 points using the distribution-based method and 1.50, 10.50, 8.34, and 3.03 points using the anchor-based method. The SCB of VAS, AOFAS, SF-36 PCS, and SF-36 MCS in PCFD surgery were 2.50, 18.50, 11.88, and 6.34 points, respectively. Moreover, the preliminary internal validation efforts have demonstrated the practical application and clinical utility of these findings. With the exception of the distribution-based MCID of SF-36 PCS, which showed fair agreement, all other measures demonstrated moderate to almost perfect agreement. ConclusionsThe MDC, MCID, and SCB intuitively enhance the interpretation of VAS, AOFAS, and SF-36 in PCFD surgery, assisting all stakeholders to better understand the therapeutic benefits and limitations of clinical care, and thus to make a more rational decision. Each of these parameters has its own emphasis and complements the others. These parameters are recommended for evaluating the clinical relevance of the results, and their promotion should extend to other areas of foot and ankle surgery.

Conservative Treatment with Arch Support Inflatable Ankle-Foot Orthosis Does Not Correct Progressive Collapsing Foot Deformity: A Prospective Comparative and Controlled Study

Category: Midfoot/Forefoot; Hindfoot Introduction/Purpose: Progressive Collapsing Foot Deformity (PCFD) can present with independent deformities, characterized by five classes: hindfoot valgus (Class A), midfoot abduction (Class B), forefoot varus (Class C), Peritalar Subluxation (PTS) (Class D) and ankle valgus (Class E). Conservative treatment includes the use of corrective insoles and orthotics. Arch support inflatable Ankle-Foot orthoses (IAFO) can help control symptoms in PCFD patients. However, the ability of IAFOs to correct deformities in PCFD is unknown. The aim of this prospective comparative and controlled study was to assess the ability of arch support IAFOs to correct 3D overall PCFD alignment as well as the five different PCFD classes independently. We hypothesized that IAFOs would correct PCFD 3D overall alignment as well as the five independent classes of deformity. Methods: After IRB approval, we enrolled 24 symptomatic PCFD and 24 controls matched on age, sex, and BMI. Flexible PCFD patients and controls were scanned using Weight-Bearing CT (WBCT) with and without an arch support IAFO. The Foot and Ankle Offset (FAO) was used to assess the 3D foot overall alignment. We measured the Hindfoot moment arm (HMA, Class A), the Talonavicular coverage angle (TNCA, Class B), the Meary’s angle and medial cuneiform-to-floor distance (C1-floor) for the Class C and the middle facet uncoverage (MFunco, Class D). No Class E patients were included. Measurements were performed by two fellowship-trained surgeons. A power-analysis hypothesizing that IAFOs would be two times less efficient than the PCFD surgery in correcting the FAO, the requisite number of subjects was 24 per group. Data normality was assessed by Shapiro-Wilk test. Comparisons used normality based paired T-tests or paired-Wilcoxon tests. P-values &lt; 0.05 were considered significant. Results: PCFD measurements performed in controls were all significantly less pronounced than unbraced PCFD patients, confirming the presence of collapse (ps &lt; 0.0001). Comparing PCFD without and with IAFO, the FAO did not show significant improvement (respectively 6.6+/-3.7% vs 5.5+/-4.2%, p=0.101). The HMA (8.8+/-5.8 vs 8.1+/-5.8, p=0.66), the TNCA (24.2+/-10.6 vs 21.9+/-9.7, p=0.44) and the MFunco (37+/-12% vs 31+/-18%, p=0.17) also did not portray significant improvements when applying the IAFOs. The Meary’s angle (17.6+/-7.2 vs 10.8+/-7.3, p=0.002) and C1-floor (17.2+/-3.3mm vs 24.1+/-5.3mm, p&lt; 0.001) were the only to improve significantly with use of IAFOs. When comparing braced PCFD and controls, the only measurement that improved to normal values, similar to controls, in braced PCFD was the C1-floor (24.1+/-5.3mm in PCFD with IAFO vs 25.7+/- 5.4mm in controls, p=0.31). Conclusion: In this prospective comparative and controlled study, we found that arch support IAFOs was not able to correct overall 3D deformity and most of the specific classes in PCFD. The orthosis did not improve hindfoot valgus (Class A), midfoot abduction (Class B) or peritalar subluxation (Class D) in PCFD. The only deformity pattern to improve with the use of IAFOs was the medial longitudinal arch height (Class C). These improvements were expected by the presence of the inflatable bladder of the IAFO on the plantar aspect of the foot, pushing the longitunal arch up but not correcting the entire PCFD.

Cervical Ligament Insufficiency in Progressive Collapsing Foot Deformity: It May Be More Important Than We Know

Category: Hindfoot; Midfoot/Forefoot Introduction/ Purpose: Subluxation at the subtalar joint is one of the major radiographic features that characterize progressive collapsing foot deformity (PCFD). Although it is recognized that the cervical ligament plays an important function in maintaining the subtalar joint's stability, its role and involvement in PCFD is largely unknown. The purpose of this study was to assess the prevalence of cervical ligament insufficiency in patients with PCFD and to establish if its integrity of it changes with increasing axial plane deformity. We hypothesized that there will be a higher prevalence of cervical ligament insufficiency in a PCFD cohort compared to that of a control group. Additionally, we hypothesized that those with higher degrees of cervical ligament insufficiency will have a more severe abduction deformity and talocalcaneal subluxation. Methods: This study retrospectively reviewed magnetic resonance imaging (MRI) of 78 PCFD patients and age- and gender- matched controls. A radiologist specializing in musculoskeletal disorders evaluated the structural derangement of the cervical ligament into five grades (Grade 0 indicating normal and Grade 4 indicating a tear greater than 50% of the cross-sectional area), as previously described. To compare its involvement in PCFD, two commonly involved ligaments (spring and interosseous) in PCFD were also evaluated. Plain radiographic parameters, including the talonavicular coverage angle (TNC), lateral talo-1st metatarsal (Meary’s) angle, calcaneal pitch, and hindfoot moment arm, as well as axial plane orientation of the talus (TM-Tal) and calcaneus (TM-Calc) relative to the transmalleolar axis and talocalcaneal subluxation (Diff Calc-Tal), were correlated with the cervical ligament MRI grading system. Results: The overall distribution of the degree of cervical ligament involvement was significantly different between the PCFD and control groups (P &lt; .001, Table 1). MRI evidence of a tear (Grades 3 or 4) in the cervical ligament was identified in 47 of 78 (60.3%) feet in the PCFD group, which was significantly higher than the control group (10.9%) and greater than that of superomedial spring (43.6%) and talocalcaneal interosseous (44.9%) ligaments. Univariate ordinal logistic regression modelling demonstrated a predictive ability of TM-Calc (Odds ratio [OR]: 1.17, 95% confidence interval [CI]: 1.06-1.30, p=.004), Diff Calc- Tal (OR: 1.15, 95% CI: 1.06-1.26, p=.002), TNC (OR: 1.08, 95% CI: 1.03-1.13, p=.003), and Meary’s angle (OR: 1.05, 95% CI: 1.02-1.10, p=.006) in determining higher cervical ligament grade on MRI (Figure 1). Conclusion: We found that cervical ligament insufficiency is a significant component of PCFD and is more common than anticipated in this study. Based on the radiographic findings in the current study, cervical ligament insufficiency appears to be primarily associated with axial plane midfoot and hindfoot deformity. If its biomechanical properties are established in the future studies, we think the reconstruction of the cervical ligament may be a potential adjunct surgical procedure for PCFD patients with significant axial plane deformity.

Comparing Symptomatic and Asymptomatic Flatfeet Using Known Markers of Progressive Collapsing Foot Deformity (PCFD): A Case Control Study

Category: Midfoot/Forefoot; Hindfoot Introduction/Purpose: Flattening of the longitudinal arch of the foot (Flatfoot) can represent a normal spectrum of foot morphology and alignment. The issue comes when the foot is collapsing progressively, what is now termed Progressive Collapsing Foot Deformity (PCFD). Literature on asymptomatic flatfoot is scarce since asymptomatic patients do not seek medical attention. Alignment differences between asymptomatic flatfoot and PCFD have not been established and might represent a key-step in understanding predictors of PCFD. The objective of this prospective study was to compare established PCFD measures in a cohort of asymptomatic flatfoot, PCFD patients and healthy controls. We hypothesized that asymptomatic flatfeet alignment would differ from both symptomatic PCFD patients and healthy controls. Methods: In this prospective comparative study, patients with asymptomatic flatfeet were recruited to undergo a weight-bearing CT (WBCT) scan. This cohort (22 feet, 10 males, 12 females) was compared to two other prospective cohorts (22 symptomatic PCFD and 22 healthy controls). Along with demographic data, PCFD measurements performed include Foot and Ankle Offset (FAO), Forefoot Arch Angle (FAA), Middle Facet Uncoverage, and the Transverse Arch Plantar (TAP) angle. Normality of variables was assessed using the Shapiro-Wilk test. Chi-squared or analysis of variance (ANOVA) test was performed to compare each parameter between the three groups. A post-hoc Bonferroni test was then performed to assess significance between each group pairing. P-values of &gt;0.05 were considered significant. Results: All three groups were comparable on BMI (p=0.10), Age (p=0.75) and Gender (p=0.78). All measurements taken differed significantly between the symptomatic PCFD and healthy controls (Table 1). FAO was significantly different between controls vs asymptomatic (p &lt; 0.001) and asymptomatic vs symptomatic (p &lt; 0.001). FAA was also significantly different between asymptomatic and both symptomatic (p=0.001) and control groups (p=0.001). Middle facet uncoverage differed between the asymptomatic and control group (p=0.001) but the asymptomatic and symptomatic group were similar (p=0.106). While the TAP angle was significantly different between asymptotic and symptomatic groups (p=0.013), the asymptomatic and control groups failed to reach significance (p=0.061) (Table 1). On average, deformity measurements for asymptomatic flatfeet were in between the values for healthy controls and symptomatic PCFD (Figures 1-3). Conclusion: To our knowledge this is the first prospective study to compare healthy controls, asymptomatic flatfoot and symptomatic PCFD patients. We observed that asymptomatic flatfoot patients usually had measurements of PCFD that would fall in between normal alignment asymptomatic controls and symptomatic PCFD patients. Further, the asymptomatic group differed significantly from both other groups on every measure but two. Our data supports the idea that asymptomatic flatfoot should be considered a risk factor for Progressive Collapsing Foot Deformity. Our data can hopefully shine light in finding predictive markers for the development of PCFD.

Three-Dimensional Distance Map Comparisons between Asymptomatic and Symptomatic Progressive Collapsing Foot Deformity (PCFD)

Category: Hindfoot Introduction/Purpose: Progressive collapsing foot deformity (PCFD) is a complex three-dimensional foot deformity that is characterized, in part, by peritalar subluxation (PTS). The subtalar joint has been analyzed in PCFD using distance mapping as a measure of subfibular impingement (Figure 1). However, the progression of PCFD from healthy to asymptomatic to symptomatic and painful, specifically within the subtalar joint, is largely unknown. Therefore, investigating asymptomatic PCFD may offer clinical insight into both the pathology of PCFD within the subtalar joint and how the disease progresses. The objective of this study was to use a three-dimensional distance mapping algorithm of the subtalar joint for asymptomatic PCFD patients to describe and compare this stage of the deformity with a previously described cohort of symptomatic PCFD patients and healthy controls. Methods: In this prospective comparative study, patients with asymptomatic flatfeet were recruited to undergo a weight-bearing CT (WBCT) scan. This cohort (20 feet, 8 male, 12 female) was compared to a previously described cohort of both control (n=10, 4 male, 6 female) and symptomatic PCFD (n=20, 8 male, 12 female). Using a commercially available software package (Disior Bonelogic), models of the talus and calcaneus were created and analyzed. Distance mapping was then used to measure the distance along the normal direction of vectors projected from the calcaneal subchondral surface to the opposing talar surface. In this manner, the subtalar joint was objectively measured across the entire peritalar surface, including articular and nonarticular regions (Figure 1). Mean distances over the described articulations of the subtalar joint were compared using an analysis of variance (ANOVA) test to compare each parameter between the three groups. Results: Regarding mean distance values, the asymptomatic group was significantly higher than symptomatic measures in 10/13 articular surfaces and 3/4 sinus tarsi regions. Asymptomatic distances were also significantly greater than control measures in 11/13 articular surfaces (Table 1, Table 2) but were smaller and without significance in the sinus tarsi region. (Table 3). When looking at the sinus tarsi as a whole, asymptomatic distances (mean 3.21mm) were greater than both control (mean 2.73mm, p=0.01,) and symptomatic distances (mean 2.63, p=0.002) (Table 1). More specifically, asymptomatic distances were different than both symptomatic and control distances in the anteromedial, posteromedial and posterolateral regions of the sinus tarsi (Table 3). Conclusion: To our knowledge, this is the first study to examine the asymptomatic flatfoot within the subtalar joint. Asymptomatic distances were found to be largely greater than both symptomatic and control distances. This suggests that the bones are unstable and moving in patients who have flatfeet but no symptoms. When PTS, in an unstable asymptomatic foot, produces sinus tarsi impingement, that may be the trigger to further collapse and subsequent pain. Our data supports the idea that asymptomatic flatfoot should be considered a risk for progression to PCFD and represents a step toward finding predictors for development painful flatfoot.

Ankle Radiographic Characteristics of Two Different Types of Valgus Ankle Arthritis: With or Without Progressive Collapsing Foot Deformity

Category: Ankle Arthritis; Ankle Introduction/Purpose: Establishing a surgical plan for ankle arthritis requires a thorough understanding of the deforming forces involved. While ankle morphology-based classification and application are common in the surgical treatment of varus ankle arthritis (i.e., Takakura stage), such an approach has not been described for valgus ankle arthritis. Progressive collapsing foot deformity (PCFD) has been identified as the major cause of non-traumatic valgus ankle arthritis. However, mounting evidence suggests that it can also develop without PCFD, which may mean that the etiology and possibly the outcomes of treatment are different when comparing the two groups. Therefore, this study aimed to investigate whether weightbearing ankle radiographs can be used to differentiate PCFD origin from non-PCFD origin in valgus ankle arthritis. Methods: This study retrospectively reviewed patients who were surgically treated for asymmetric valgus ankle arthritis at our institution between 2017 and 2021. Patients with valgus tibiotalar tilt (TT &gt;4 degrees and Meary’s angle&gt;30 degrees) were included in the PCFD group (n=24). A control group (non-PCFD group [n=24]) with valgus tibiotalar tilt&gt;4 degrees and Meary’s angle &lt; 4 degrees was also established. In the weightbearing ankle anteroposterior (AP) view, the TT and medial distal tibial angle (MDTA) were measured. Additionally, to assess mediolateral position of the talus, the talar center migration (TCM) and lateral talar dome-plafond distance (LTD-P) ratio was measured (Figure 1A). Other PCFD radiographic parameters were also measured. In weightbearing computed tomography (WBCT), the degree of axial plane talocalcaneal subluxation was assessed using transmalleolar axis method as previously described, and the prevalence of sinus tarsi bony impingement was assessed. All parameters were compared between groups using Student t- or chi-square tests. Results: Both groups demonstrated a similar degree of TT, with a mean and standard deviation of 11.1±7.8 degrees in the PCFD group and 12.7±5.9 degrees in the non-PCFD group (p=0.2013, Table 1). However, the PCFD group showed a significantly greater TCM and LTD-P ratio compared to those of the non-PCFD group (p &lt; 0.0001), indicating that PCFD patients have a more medially translated talus in ankle AP radiographs (Figure 1A). WBCT showed that the PCFD group had a greater axial plane talocalcaneal subluxation (p &lt; 0.0001) and a higher prevalence of sinus tarsi bony impingement (p=0.0077) compared to the non- PCFD group, indicating a different degree of subtalar joint subluxation between the two groups. Conclusion: This study demonstrates that weightbearing ankle radiographs reveal different morphologies based on the etiology of valgus ankle arthritis. While both groups exhibited similar degrees of valgus tibiotalar tilt, PCFD patients demonstrated medial translation of the talus compared to non-PCFD patients. We propose a morphology-based classification (Figure 1B) that may assist in differentiating between the PCFD and non-PCFD origins of valgus ankle arthritis. Also, the different morphology of the valgus tibiotalar tilt in the each group may mean that they may require different treatments, as well as potentially different outcomes of treatment for the valgus tibiotalar tilt.